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Possible Semaglutide Side Effects

The primary beneficial effects of semaglutide:

  • Decreased appetite

  • Decreased cravings

  • Decreased in symptoms and risk of all health issues related to obesity, ie: hypertension, stroke, cardiac disease and many others. 


Some effects, good/bad? 

  • Decreased cravings for alcohol, tobacco and drugs *

  • Decrease cravings altogether​

Current studies include use of GLP-1A in treatment for drug addictions. ​

The most common adverse side effects reported:

  • Nausea - Usually experienced with initial dose and when initial during dose increase steps

  • Vomiting - Not as common

  • Heartburn - More common in those who have pre-existing acid reflux diagnosis

  • Constipation - More common. Many report the need for a daily fiber supplement 

  • Diarrhea - Not as common. Contact your provider if diarrhea greater than 24 hours.

  • Abdominal cramping - More common when initial dose during dose increase steps



Rare but serious adverse side effects

  • Pancreatitis

  • Gallstones

  • Worsening of diabetic retinopathy

  • Kidney damage

  • Thyroid tumors

Although the above are rare adverse side effects, having a history of pancreatitis, gallbladder disease, diminished renal function or any history in yourself or immediate family of medullary thyroid cancer or multiple endocrine neoplasia (MEN) type 2 are clinical indicators that you should not attempt to use any GLP-1A medication. ​ Anyone with the above pre-existing diagnosis will not be prescribed semaglutide from this clinic. 

* Source: National Institute of Health 

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